Journal article
Reticular Pseudodrusen: Interreader Agreement of Evaluation on OCT Imaging in Age-Related Macular Degeneration
Z Wu, S Schmitz-Valckenberg, BA Blodi, FG Holz, GJ Jaffe, S Liakopoulos, SR Sadda, M Bonse, T Brown, J Choong, B Clifton, G Corradetti, F Corvi, AC Dieu, V Dooling, JW Pak, M Saßmannshausen, C Skalak, S Thiele, RH Guymer
Ophthalmology Science | Published : 2023
Abstract
Purpose: To determine the interreader agreement for reticular pseudodrusen (RPD) assessment on combined infrared reflectance (IR) and OCT imaging in the early stages of age-related macular degeneration across a range of different criteria to define their presence. Design: Interreader agreement study. Participants: Twelve readers from 6 reading centers. Methods: All readers evaluated 100 eyes from individuals with bilateral large drusen for the following: (1) the presence of RPD across a range of different criteria and (2) the number of Stage 2 or 3 RPD lesions (from 0 to ≥ 5 lesions) on an entire OCT volume scan and on a selected OCT B-scan. Supportive information was available from the corr..
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Grants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
Supported by National Health & amp; Medical Research Council of Australia (grant no.: GNT1181010 [R.H.G. and Z.W.] , #1194667 [R.H.G.] , and #2008382 [Z.W.] ) , a grant from the Macular Disease Foundation Australia (Z.W. and R.H.G.) , in part by an unrestricted grant from Research to Prevent Blindness Inc to the University of Wisconsin-Madison Department of Ophthalmology and Visual Sciences (B.B.) and to the Department of Ophthalmology & amp; Visual Sciences, University of Utah (S.S.V.) , and by the BONFOR GEROK Program, Faculty of Medicine, University of Bonn, Grant No O-137.0030 (M.S.) . CERA receives operational infrastructure support from the Victorian Government. The sponsor or funding organization played no role in the design or conduct of this research.